GI Disease

Researchers in HK conducted a retrospective cohort study on patients with aspirin-associated lower GI bleeding between 2000 and 2007. They were identified and clinical data of 295 patients were analyzed. Patients were divided into 2 groups (the Non-user group and Aspirin group) according to their cumulative exposure to aspirin during a 5-year period.
The results showed that among aspirin users with a history of lower GI bleeding, discontinuation of aspirin would lead to a 61% increase in serious cardiovascular events including nonfatal myocardial infarction, nonfatal stroke, or death from vascular causes, while the risk of recurrent lower GI bleeding decreased by 63%.

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